You're looking at permalinked Calvin and Markov strip #293529454464156480.
Calvin and Markov digests Calvin and Hobbes strips and generates new comics using Markov chains, perl, and Imagemagick.
Want to know the details? Here's some info on how it works.
If you like this sort of thing, you might also take a look at Garkov, Previously, On The X-Files, The Big Markovski, and Jesus Markoving Christ.